Making One's Own Molecule 01 (Straight Iso E Super)

David Ruskin

Well-known member
May 28, 2009
IFRA recommend a maximum of 21.0% on unshaved skin, and (I think) a maximum of 7.0% on shaved skin. These recommendations are due to Iso E Super being considered a sensitiser.
 

I.D.Adam

Well-known member
Nov 14, 2014
FWIW, I decided to wear Iso E Super today at 10% dilution to evaluate it on skin. I don't know why anyone would wear this by itself as a fragrance but I didn't note any irritation. To each their own I suppose :)
 

pkiler

Basenotes Plus
Basenotes Plus
Dec 5, 2007
I think that 100% Iso E Super might have trouble just going through a sprayer due to viscosity...
You should predilute... And you don't really need to have it at more than 20% dilution anyway.
 

Chris Bartlett

Basenotes Plus
Basenotes Plus
Jul 17, 2011
Hi everybody,

I'm new to this forum and I also decided to try and make my own Molecule 01 as DIY has always been fun for me and I really don't have enough money to buy expensive originals :)

I've already ordered Iso E Super and Perfumers alcohol (the only one I was able to get in my country contained denatured alcohol, isopropyl myristate and dpgl) and I have also read the Primer, however I do have couple of questions and I would be really glad if someone more knowledgable than me would help me with them.

1. I purchased a couple of aluminium bottles with atomizers, do I need to sterilize them in the oven as well prior to filling (of course, without atomizers, hehe)?

2. I don't understand the "sitting" process entirely, after mixing iso e super and alcohol, do I need to leave it open or close it in glass container for several weeks? Or can I just fill the aluminium bottles and let it rest in them? As somebody else pointed out, is it really necessary to wait for 4-6 weeks with just mixing iso e super and perfumers alcohol? Also, after sitting period, do I need to add distilled water to the mix and filter thru coffee filter?

Thanks in advance for answers.

Cheers, Thomas.

Whatever you do don't waste your IES trying to spray it neat because it's too thick to spray. A 20% solution in ethanol is fine and there's no need to let it rest, it will be fit to use right after mixing.
 

jsparla

Well-known member
Jun 5, 2011
Is this a good set to make Molecule 01?

I'm not sure about the "Cosmetisch Haarwater"...

http://www.hekserij.nl/Parfum_en_Geur/Pakketten_(geur_en_parfum)/MAKKELIJK_Parfum_No1_maken.aspx

23021-4 Iso E Super 10 ml
27001-1 Verstuiver Quadro 30 ml
27092-1 Miniverstuiver helder
29550-7 Cosmetisch Haarwater 100 ml
30110-1 Druppelpipet plastic 3 ml
30111-1 Druppelpipet plastic 1 ml
Werkblad

Yes, this is a good supplier, and Cosmetisch Haarwater can be used: it's 97% alcohol, a bit of panthanol and bergamot (hardly noticeable, but undrinkable).
And if you'd like to get some more fun out of your Iso E Super Molecule One project, take a look at some 'upgrades', ten variations on a theme ;-)
https://sites.google.com/site/perfu...centric-molecule-01-ten-variations-on-a-theme

Happy perfuming.
 

Chris Bartlett

Basenotes Plus
Basenotes Plus
Jul 17, 2011

antoniovidaljr

New member
Sep 30, 2016
Hi everyone!

I have a few questions.

1. Can i use this to make molecule 01? Ethanol 95% Denatured with 5.0% IPA containing 690mg of Bitrex per 100L of alcohol.

2. Iso E Super (i)
CAS # 54464-57-2
Can use up to 10% of total concentrate.
If I wanted to make 20% concentrate in 100ml bottle, how could I do it?
Does the "Can use up to 10% of total concentrate." Mean its not 100% Iso E Super?

Stupid questions but your help is appreciated.
Glad to be here. :)
 

pkiler

Basenotes Plus
Basenotes Plus
Dec 5, 2007
Probably, you can use the alcohol. Go ahead and try a 20% dilution, of 20 grams Iso E Super, and 80 grams alcohol.
 

antoniovidaljr

New member
Sep 30, 2016
Probably, you can use the alcohol. Go ahead and try a 20% dilution, of 20 grams Iso E Super, and 80 grams alcohol.

Thank you for your help.

I was wondering if the Iso E from Perfumers Apprentice has always been only 10% of concentrate or more? The reason I'm asking is if it's only 10% than if I'm trying to make a 100ml bottle like you said than I would only have 2% concentrate of Iso E in the whole bottle.
Is 2% enough to smell like Molecule 01?
Thanks
 

Possum-Pie

Well-known member
Jun 10, 2012
I tell people that if they are just out to save money, there are a few people online who make Iso E Super fragrance similar to Molecule 01 and sell it on EBAY for less than $20. It's much easier than trying to get it right yourself. If you are interested in doing it yourself for the enjoyment of it, then by all means, have fun! I bought a bottle 2 years ago from a chap in England, and even with shipping cost to USA, it was less than $20 for 50mls...I just peeked on Ebay, and he is still selling. I see some folks from the USA have also gotten into the game, but can't vouch for their quality, I've never tried theirs.
 

gandhajala

Well-known member
Sep 3, 2010
Hi everyone!

I have a few questions.

1. Can i use this to make molecule 01? Ethanol 95% Denatured with 5.0% IPA containing 690mg of Bitrex per 100L of alcohol.

2. Iso E Super (i)
CAS # 54464-57-2
Can use up to 10% of total concentrate.
If I wanted to make 20% concentrate in 100ml bottle, how could I do it?
Does the "Can use up to 10% of total concentrate." Mean its not 100% Iso E Super?

Stupid questions but your help is appreciated.
Glad to be here. :)

I think that is a usage guideline.
Also, as I am sure has been pointed out in this thread, Molecule 01 uses Iso Gamma Super which is captive. That means, your home-brew Iso E Super version will not smell identical. I think the consensus is that Timbersilk is closer to Iso Gamma than regular qualities of Iso E.
 

David Ruskin

Well-known member
May 28, 2009
Thank you for your help.

I was wondering if the Iso E from Perfumers Apprentice has always been only 10% of concentrate or more? The reason I'm asking is if it's only 10% than if I'm trying to make a 100ml bottle like you said than I would only have 2% concentrate of Iso E in the whole bottle.
Is 2% enough to smell like Molecule 01?
Thanks

20 gms plus 80 gms alcohol adds up to 100 gms; that is a 20.0% solution of Iso E Super in alcohol.
 

David Ruskin

Well-known member
May 28, 2009
IFRA recommends the use of Iso E Super at a maximum of 7.1% in final product for Aftershaves (applied to abraded skin) and 21.3% for all other alcoholic applications.
 

antoniovidaljr

New member
Sep 30, 2016
Thanks everyone. I want to have fun making my own perfume, but I do love the way Molecule 01 smells. I just bought a bottle here in Canada $185 plus taxes $210. I don't regret it because their is something magical about it. I want to try to play with that scent and tinker with it and make it my own.
How much timbersilk would you add to 100ml bottle with 20% Iso E?
You know how it takes 10min or so to start smelling Molecule 01, would adding timbersilk make it smell right away?
 

lyoffka

Well-known member
Jun 26, 2015
Guys, all my mixes of iso e super have extremely alcoholic opening.( What do you think, how do Molecules handle the problem? Can hedione or anything else help?
 

the_good_life

Basenotes Plus
Basenotes Plus
Jun 2, 2006
I have a serious question thoiugh. What do you all think about if I went hard, and sprayed straight 100% ISO E Super out of the atomizer, straight onto my skin, instead of diluting it down. I'm liukely at least going to give that a try, I dont know how much i'll experiment in the 100% atomizer, maybe 10ml.

Jackass - perfumery edition :-D
 

Possum-Pie

Well-known member
Jun 10, 2012
Guys, all my mixes of iso e super have extremely alcoholic opening.( What do you think, how do Molecules handle the problem? Can hedione or anything else help?

Ethanol at 96% or higher generally doesn't smell of "alcohol" more than a few seconds...if it is sticking around longer than that it may be contaminated, or you may be smelling some component of the I. E . Super...
 

lyoffka

Well-known member
Jun 26, 2015
I guess you are right about the contamination, cause I am using 96% medical alcohol since it's the only available option in my country. I guess I should try perfumers alcohol.
 

Possum-Pie

Well-known member
Jun 10, 2012
I guess you are right about the contamination, cause I am using 96% medical alcohol since it's the only available option in my country. I guess I should try perfumers alcohol.

Ah..that is probably the answer. ISOPROPYL alcohol is acceptable for fragrances, but the odor is more noxious and lasts longer. You can try a top note to mask the Isopropyl. It will disappear about the same time the isopropyl smell will.
 

I.D.Adam

Well-known member
Nov 14, 2014
Ah..that is probably the answer. ISOPROPYL alcohol is acceptable for fragrances, but the odor is more noxious and lasts longer. You can try a top note to mask the Isopropyl. It will disappear about the same time the isopropyl smell will.

Because of it's smell, and potential for noxious side effects if ingested, isopropyl alcohol is NOT acceptable for fragrance.
 

Possum-Pie

Well-known member
Jun 10, 2012
Because of it's smell, and potential for noxious side effects if ingested, isopropyl alcohol is NOT acceptable for fragrance.

You are correct...I shouldn't have said "Acceptable" in terms of preferred, it is NOT preferred. Acceptable as in it will work if you are OK with the odor and there is no other alternative diluant. As for ingestion, none of the fragrances are meant for drinking, so that is a non-issue. My shampoo will make me sick if I drink it...doesn't stop me from using it.
 

I.D.Adam

Well-known member
Nov 14, 2014
You are correct...I shouldn't have said "Acceptable" in terms of preferred, it is NOT preferred. Acceptable as in it will work if you are OK with the odor and there is no other alternative diluant. As for ingestion, none of the fragrances are meant for drinking, so that is a non-issue. My shampoo will make me sick if I drink it...doesn't stop me from using it.

It is a potential liability issue and it would be very unwise to use isopropyl alcohol in a commercial fragrance.
 

Possum-Pie

Well-known member
Jun 10, 2012
It is a potential liability issue and it would be very unwise to use isopropyl alcohol in a commercial fragrance.

Absolutely...but many BNers come to DIY asking about isopropyl b/c they are trying to make frags for their own use, in countries where Ethanol is Banned/impossible to get. Rather than saying "You can't use isopropyl" I give them the pros and cons and let them decide. Lyoffka stated that Ethanol is unavailable and he is using "medical" alcohol...I'm assuming that is Isopropyl. As long as he doesn't sell it, and is ok with the smell, he can use it.
 

lyoffka

Well-known member
Jun 26, 2015
As long as he doesn't sell it, and is ok with the smell, he can use it.

I am not ok with it, and I'll try the alternatives as soon as I figure it out how to import it. But I dont understand, what is the problem with usage the Isopropyl in the commercial fragrances? I mean besides the odor issues.
 

Erica lawrence

New member
Jan 9, 2022
OK first up, not all Iso E Super is the same, but if you buy the stuff from PA then it should be the original from IFF so that’s a good start - you might want to check that’s still what they are stocking before you buy as there are cheaper alternatives on the market that won’t perform as well (it’s the proportion of the gamma isomer that’s critical if you’re into chemical specifics).

Second don’t forget that what you get will be a pure chemical so handle with care.

Perfumer’s Alcohols are not all the same either, and you might want to consider using Everclear 95% ethanol if it’s available in Oregon as that way you are not introducing any other chemicals to the blend at all. Failing that choose the most neutral form of ethanol you can buy but don’t go for anything with more than around 5% water in it.

Finally I don’t know for sure what proportion is used in Molecule 01 but I would suggest you start with a 10-15% solution and certainly don’t go higher than about 20%. Ideally that should be by weight, but as you’re starting out you probably won’t have scales so what you need to know is this:
The specific gravity of Iso E Super is between 0.96 and 0.97.
The specific gravity of ethanol is roughly 0.8

So to get 100ml of a ~10% solution you’d need to put in 8ml of Iso E Super to 92ml of ethanol:
8 x .96 = 7.68
92 x .8 = 73.6

So that’s a 10.4% solution by weight - close enough for your purposes. If you don’t find that’s strong enough you can always add more Iso E Super until you’re happy with it.
Any shop or online store where I can get these items?
 

pkiler

Basenotes Plus
Basenotes Plus
Dec 5, 2007
Any shop or online store where I can get these items?
The source that you quote mentions PA as a source, which is Perfumer's Apprentice, in California.
Other suppliers that you can purchase from are Perfumer Supply House in Connecticut, and Creating Perfume, (But they just moved across the country to the US East Coast, and I can't remember where they are presently...)
 

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